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Viral targets for vaccines against COVID-19.


ABSTRACT: Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic and to help the return to pre-pandemic normalcy. A great many vaccine candidates are being developed, several of which have completed late-stage clinical trials and are reporting positive results. In this Progress article, we discuss which viral elements are used in COVID-19 vaccine candidates, why they might act as good targets for the immune system and the implications for protective immunity.

SUBMITTER: Dai L 

PROVIDER: S-EPMC7747004 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Viral targets for vaccines against COVID-19.

Dai Lianpan L   Gao George F GF  

Nature reviews. Immunology 20201218 2


Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic and to help the return to pre-pandemic normalcy. A great many vaccine candidates are being developed, several of which have completed late-stage clinical trials and are reporting positive results. In this Progress article, we discuss which viral elements are used in COVID-19 vaccine candidates, why they might act as good targets for the immune system and the implications for protective immunity. ...[more]

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