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ABSTRACT: Background
Adverse childhood experiences are prevalent robust risk factors for the development of substance use problems. However, less is known about the causal mechanisms that explain these relationships. While directly preventing adverse childhood experiences is ideal, it is not always possible. In such cases, the mechanisms themselves may be amenable to intervention, allowing for the effective prevention of problematic substance use among children exposed to adversity. Identifying such mechanisms is therefore a critical step for efforts aiming to reduce the high individual and societal burdens associated with substance use globally.Objective
This study aims to systematically identify and synthesize evidence on the modifiable mediators and moderators of the relationship
SUBMITTER: Grummitt LR
PROVIDER: S-EPMC7748964 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature