Otitis media with effusion in Africa-prevalence and associated factors: A systematic review and meta-analysis.

ABSTRACT:

Objectives

To estimate the overall and subgroup prevalence of otitis media with effusion (OME) in Africa, and identify setting-specific predictors in children and adults.

Methods

PubMed, African Journals Online, African Index Medicus, Afrolib, SciELO, Embase, Scopus, Web of Science, The Cochrane Library, GreyLit and OpenGray were searched to identify relevant articles on OME in Africa, from inception to December 31st 2019. A random-effects model was used to pool outcome estimates.

Results

Overall, 38 studies were included, with 27 in meta-analysis (40?331 participants). The overall prevalence of OME in Africa was 6% (95% CI: 5%-7%; I ² =?97.5%, P?P = .02). Other significant associated factors were age, adenoid hypertrophy, allergic rhinitis in children, and type 2 diabetes mellitus, low CD4 count in adults.

Conclusion

OME prevalence was similar to that reported in other settings, notably high-income temperate countries. Health care providers should consider age, presence of cleft palate, adenoid hypertrophy and allergic rhinitis when assessing OME in children and deciding on a management plan. More research is required to confirm risk factors and evaluate treatment options.

Level of evidence

3a.

SUBMITTER: Choffor-Nchinda E 

PROVIDER: S-EPMC7752044 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature