Ontology highlight
ABSTRACT:
SUBMITTER: Warnecke A
PROVIDER: S-EPMC7752163 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Clinical and translational medicine 20201201 8
The lack of approved anti-inflammatory and neuroprotective therapies in otology has been acknowledged in the last decades and recent approaches are heralding a new era in the field. Extracellular vesicles (EVs) derived from human multipotent (mesenchymal) stromal cells (MSC) can be enriched in vesicular secretome fractions, which have been shown to exert effects (eg, neuroprotection and immunomodulation) of their parental cells. Hence, MSC-derived EVs may serve as novel drug candidates for sever ...[more]