Unknown

Dataset Information

0

Therapeutic advances of miRNAs: A preclinical and clinical update.


ABSTRACT: miRNAs, a class of small endogenous RNAs, are one of the essential biopharmaceuticals which are in commercial spans as next-generation medicine in recent times. A snapshot of the current scenario regarding the miRNAs as biopharmaceuticals have been discussed. In this work, biopharmaceutical companies working with miRNAs and the current status of preclinical/clinical trials about miRNA therapeutics have been reviewed. Finally, recent updates on the absorption, distribution, metabolism, and excretion (ADME), as well as a delivery system of miRNAs, have been illustrated.

SUBMITTER: Chakraborty C 

PROVIDER: S-EPMC7753224 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

altmetric image

Publications

Therapeutic advances of miRNAs: A preclinical and clinical update.

Chakraborty Chiranjib C   Sharma Ashish Ranjan AR   Sharma Garima G   Lee Sang-Soo SS  

Journal of advanced research 20200829


miRNAs, a class of small endogenous RNAs, are one of the essential biopharmaceuticals which are in commercial spans as next-generation medicine in recent times. A snapshot of the current scenario regarding the miRNAs as biopharmaceuticals have been discussed. In this work, biopharmaceutical companies working with miRNAs and the current status of preclinical/clinical trials about miRNA therapeutics have been reviewed. Finally, recent updates on the absorption, distribution, metabolism, and excret  ...[more]

Similar Datasets

| S-EPMC5715130 | biostudies-literature
| S-EPMC5722794 | biostudies-literature
| S-EPMC9563739 | biostudies-literature
| S-EPMC3655447 | biostudies-other
| S-EPMC5701918 | biostudies-literature
| S-EPMC6678980 | biostudies-literature
| S-EPMC7469991 | biostudies-literature
| S-EPMC7736171 | biostudies-literature
| S-EPMC8616406 | biostudies-literature
| S-EPMC4410780 | biostudies-other