Gastrointestinal and hepatic manifestations of COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Background and aim

This review investigates the role of gastrointestinal and hepatic manifestations in COVID-19, particularly with regard to the prevalence of isolated gastrointestinal (GI) symptoms.

Methods

We searched PubMed, Embase, and Cochrane library for COVID-19 publications from 1 December 2019 to 18 May 2020. We included any study that reported the presence of GI symptoms in a sample of >5 COVID-19 patients. Data collection and risk of bias assessment were performed independently by two reviewers. Where ≥3 studies reported data sufficiently similar to allow calculation of a pooled prevalence, we performed random effects meta-analysis.

Results

This review included 17 776 COVID-19 patients from 108 studies. Isolated GI symptoms only occurred in 1% (95% confiden

SUBMITTER: Dorrell RD 

PROVIDER: S-EPMC7753450 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature