Ontology highlight
ABSTRACT: Purpose
To investigate the feasibility and practicality of ultraviolet (UV) germicidal irradiation of the inner bore of a computed tomography (CT) gantry as a means of viral decontamination.Method
A UV lamp (PADNUT 38 W, 253 nm UV-C light tube) and UV-C dosimeter (GENERAL UV-C Digital Light Meter No. UV512C) were used to measure irradiance throughout the inner bore of a CT scanner gantry. Irradiance (units μW/cm2 ) was related to the time required to achieve 6-log viral kill (10-6 survival fraction).Results
A warm-up time of ~120 s was required for the lamp to reach stable irradiance. Irradiance at the scan plane (z = 0 cm) of the CT scanner was 580.9 μW/cm2 , reducing to ~350 μW/cm2 at z = ±20 cm toward the front or back of the gantry. The angular distribution of irradiation was uniform within 10% coefficient of variation. A conservative estimate suggests at least 6-log kill (survival fraction ≤ 10-6 ) of viral RNA within ±20 cm of the scan plane with an irradiation time of 120 s from cold start. More conservatively, running the lamp for 180 s (3 min) or 300 s (5 min) from cold start is estimated to yield survival fraction <<10-7 survival fraction within ±20 cm of the scan plane.Conclusion
Ultraviolet irradiation of the inner bore of the CT gantry can be achieved with a simple UV-C lamp attached to the CT couch. Such practice could augment manual wipe-down procedures, improve safety for CT technologists or housekeeping staff, and could potentially reduce turnover time between scanning sessions.
SUBMITTER: Mahesh M
PROVIDER: S-EPMC7753452 | biostudies-literature |
REPOSITORIES: biostudies-literature