Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Perosanz M
PROVIDER: S-EPMC7753581 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Gomez-Perosanz Marta M Sanchez-Trincado Jose L JL Fernandez-Arquero Miguel M Sidney John J Sette Alessandro A Lafuente Esther M EM Reche Pedro A PA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20201123 1
Human Rhinovirus (HRV) is a major cause of common cold, bronchiolitis, and exacerbations of chronic pulmonary diseases such as asthma. CD8 T cell responses likely play an important role in the control of HRV infection but, surprisingly, HRV-specific CD8 T cell epitopes remain yet to be identified. Here, we approached the discovery and characterization of conserved HRV-specific CD8 T cell epitopes from species A (HRV A) and C (HRV C), the most frequent subtypes in the clinics of various pulmonary ...[more]