Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review.
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ABSTRACT: Background and aims
The term "Food Allergy" refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders.Methods
We will undertake a systematic review, which will involve searching international biomedical databases for published studies. Studies will be independently screened against pre-defined eligibility criteria and critically appraised by established instruments. Data will be descriptively and, if possible and applicable, quantitatively synthesised.Ethics and dissemination
This study does not require any specific ethical approval since it is a systematic review. We plan to report results from this systematic review in a peer reviewed journal. These results will be used to inform the development of an international consensus to define severe food allergy. Author's potential conflicts of interest are clearly stated.Prospero registration number
CRD42020183103.
SUBMITTER: Arasi S
PROVIDER: S-EPMC7753945 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review.
Arasi Stefania S Nurmatov Ulugbek U Turner Paul J PJ Ansotegui Ignacio J IJ Daher Shahd S Dunn-Galvin Audrey A Ebisawa Motohiro M Eigenmann Philippe P Fernandez-Rivas Montserrat M Gupta Ruchi R Nowak-Wegrzyn Anna A Petrou Stavros S Roberts Graham G Sánchez Borges Mario A MA Sindher Sayantani B SB Tanno Luciana Kase LK Vazquez-Ortiz Marta M Vickery Brian P BP Wong Gary Wing-Kin GW Fiocchi Alessandro A
The World Allergy Organization journal 20201219 12
<h4>Background and aims</h4>The term "Food Allergy" refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders.<h4>Methods</h4>We ...[more]
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