Ontology highlight
ABSTRACT:
SUBMITTER: Charap AJ
PROVIDER: S-EPMC7754625 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Journal for immunotherapy of cancer 20201201 2
Head and neck squamous cell carcinoma (HNSCC) encompasses a set of cancers arising from the epithelia of the upper aerodigestive tract, accounting for a significant burden of disease worldwide due to the disease's mortality, morbidity, and predilection for recurrence. Prognosis of HNSCC in the recurrent and/or metastatic (R/M-HNSCC) setting is especially poor and effective treatment options increasingly rely on modulating T-cell antitumor responses. Still, immunotherapy response rates are genera ...[more]