Skin manifestations of COVID-19: A worldwide review.
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ABSTRACT: Objective
Because of the increasing emergence of skin manifestations of COVID-19 worldwide, we investigated the published reports of these lesions.Methods
We conducted a literature search for original and review articles published from November 11, 2019 to September 30, 2020.Results
We identified 5 skin lesions common in patients with COVID-19: pseudo-chilblains, rashes containing macules and papules, and urticarial, vesicular, and vaso-occlusive lesions. These lesions manifested at various times in relation to the COVID-19 symptoms, which may indicate whether the lesions are virus-induced or are delayed immunological responses to the infection. Skin lesions were more prevalent among Europeans and United States residents than among Asians, as was pseudo-chilblain, and the morphology of the skin lesions varied among continents. Pseudo-chilblains were the most common COVID-19 skin manifestation in Europe and the United States, but there was only 1 reported case from Asian populations. Additionally, patients with vaso-occlusive lesions were more likely than those with pseudo-chilblains to be admitted to the intensive care unit and to die.Conclusion
Different cutaneous manifestations in patients with COVID-19 could reflect a wide spectrum of viral interactions with the skin, though reporting bias may play a role as well.
SUBMITTER: Tan SW
PROVIDER: S-EPMC7754879 | biostudies-literature |
REPOSITORIES: biostudies-literature
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