Ontology highlight
ABSTRACT:
SUBMITTER: Avey S
PROVIDER: S-EPMC7755271 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Avey Stefan S Mohanty Subhasis S Chawla Daniel G DG Meng Hailong H Bandaranayake Thilinie T Ueda Ikuyo I Zapata Heidi J HJ Park Koonam K Blevins Tamara P TP Tsang Sui S Belshe Robert B RB Kaech Susan M SM Shaw Albert C AC Kleinstein Steven H SH
Journal of immunology (Baltimore, Md. : 1950) 20200214 6
The seasonal influenza vaccine is an important public health tool but is only effective in a subset of individuals. The identification of molecular signatures provides a mechanism to understand the drivers of vaccine-induced immunity. Most previously reported molecular signatures of human influenza vaccination were derived from a single age group or season, ignoring the effects of immunosenescence or vaccine composition. Thus, it remains unclear how immune signatures of vaccine response change w ...[more]