Ontology highlight
ABSTRACT:
SUBMITTER: Park K
PROVIDER: S-EPMC7755770 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Park Kuenyoul K Kim Min Kyu MK Lee Taegeun T Hong Jinyoung J Kim Hyun-Ki HK Ahn Sunyoung S Lee Young-Jae YJ Kim Jisun J Lee Shin-Wha SW Lee Jong Won JW Lee Woochang W Chun Sail S Son Byung Ho BH Jung Kyung Hae KH Kim Yong-Man YM Min Won-Ki WK Ahn Sei-Hyun SH
Journal of clinical laboratory analysis 20200819 12
<h4>Background</h4>As next-generation sequencing (NGS) technology matures, various amplicon-based NGS tests for BRCA1/2 genotyping have been introduced. This study was designed to evaluate an NGS test using a newly released amplicon-based panel, AmpliSeq for Illumina BRCA Panel (AmpliSeq panel), for detection of clinically significant BRCA variants, and to compare it to another amplicon-based NGS test confirmed by Sanger sequencing.<h4>Methods</h4>We reviewed BRCA test results done by NGS using ...[more]