Ontology highlight
ABSTRACT:
SUBMITTER: van der Aart-van der Beek AB
PROVIDER: S-EPMC7756541 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
van der Aart-van der Beek Annemarie B AB Clegg Lindsay E LE Penland Robert C RC Boulton David W DW Sjöström C David CD Mentz Robert J RJ Holman Rury R RR Heerspink Hiddo J L HJL
Diabetes, obesity & metabolism 20200915 12
The effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on renal outcomes in patients with type 2 diabetes at high cardiovascular risk are modest or neutral. However, GLP-1RAs may confer clinical benefits in those at high risk of progressive renal function loss. We examined the effects of once-weekly exenatide (EQW) on estimated glomerular filtration rate (eGFR) slope and urinary albumin:creatinine ratio (UACR) as a function of baseline UACR in 3503 EXSCEL participants (23.7%) with e ...[more]