Dynamic SARS-CoV-2-Specific Immunity in Critically Ill Patients With Hypertension.

ABSTRACT:

Background

The current outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses an unprecedented health crisis. The most common chronic illness among patients infected with SARS-CoV-2 is hypertension. Immune dysregulation plays an important role in SARS-CoV-2 infection and in the development of hypertension; however, the dynamic immunological characteristics of COVID-19 patients with hypertension remain largely unclear.

Methods

In total, 258 hypertensive patients infected with SARS-CoV-2 were included in this study. CD38⁺HLA-DR⁺ and CD38⁺PD-1⁺ CD8⁺ T cells, IFNγ⁺CD4⁺ and IFNγ⁺CD8⁺ T cells, the titers of IgG, Ig

SUBMITTER: Zeng Q 

PROVIDER: S-EPMC7758245 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature