Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants.

ABSTRACT: Childhood trauma, and in particular physical neglect, has been repeatedly associated with lower performance on measures of social cognition (e.g. emotion recognition tasks) in both psychiatric and non-clinical populations. The neural mechanisms underpinning this association have remained unclear. Here, we investigated whether volumetric changes in three stress-sensitive regions-the amygdala, hippocampus and anterior cingulate cortex (ACC)-mediate the association between childhood trauma and emotion recognition in a healthy participant sample (N = 112) and a clinical sample of patients with schizophrenia (N = 46). Direct effects of childhood trauma, specifically physical neglect, on Emotion Recognition Task were observed in the whole sample. In healthy participants, reduced total and left A

SUBMITTER: Rokita KI 

PROVIDER: S-EPMC7759212 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature