Ontology highlight
ABSTRACT:
SUBMITTER: Sumsuzzman DM
PROVIDER: S-EPMC7760393 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sumsuzzman Dewan Md DM Choi Jeonghyun J Khan Zeeshan Ahmad ZA Hong Yonggeun Y
Antioxidants (Basel, Switzerland) 20201127 12
Extensive burns result in a local wound response and distant-organ injury (DOI) caused by oxidative-stress and inflammation. Melatonin (MT) shows promise in alleviating oxidative-stress and inflammation, but its role in thermal injury is largely unexplored. The present systematic review and meta-analysis were designed to assess the effects of MT on oxidative-stress and inflammatory markers against severe burn-induced DOI. Mean difference (MD)/standard mean difference (SMD) with 95% confidence in ...[more]