Ontology highlight
ABSTRACT:
SUBMITTER: Ratti S
PROVIDER: S-EPMC7760974 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ratti Stefano S Lonetti Annalisa A Follo Matilde Y MY Paganelli Francesca F Martelli Alberto M AM Chiarini Francesca F Evangelisti Camilla C
Cancers 20201124 12
B-cell acute lymphoblastic leukemia (B-ALL) is a hematologic malignancy that arises from the clonal expansion of transformed B-cell precursors and predominately affects childhood. Even though significant progresses have been made in the treatment of B-ALL, pediatric patients' outcome has to be furtherly increased and alternative targeted treatment strategies are required for younger patients. Over the last decade, novel approaches have been used to understand the genomic landscape and the comple ...[more]