Roles, Characteristics, and Analysis of Intrinsically Disordered Proteins: A Minireview.
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ABSTRACT:
SUBMITTER: Lermyte F
PROVIDER: S-EPMC7761095 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Roles, Characteristics, and Analysis of Intrinsically Disordered Proteins: A Minireview.
Life (Basel, Switzerland) 20201130 12
In recent years, there has been a growing understanding that a significant fraction of the eukaryotic proteome is intrinsically disordered, and that these conformationally dynamic proteins play a myriad of vital biological roles in both normal and pathological states. In this review, selected examples of intrinsically disordered proteins are highlighted, with particular attention for a few which are relevant in neurological disorders and in viral infection. Next, the underlying causes for the in ...[more]
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