Synthesis of Water Resistance and Moisture-Permeable Nanofiber Using Sodium Alginate-Functionalized Waterborne Polyurethane.

ABSTRACT: The development of nontoxic and biodegradable alginate-based materials has been a continual goal in biological applications. However, their hydrophilic nature and lack of spinnability impart water instability and poor mechanical strength to the nanofiber. To overcome these limitations, sodium alginate (SA) and waterborne polyurethane (WPU) were blended and crosslinked with calcium chloride; 30 wt % of SA exhibited good compatibility. Further addition of 10 wt % calcium chloride improved the water stability to an extremely humid region. Furthermore, the stress-strain curve revealed that the initial modulus and the elongation strength of the WPU/SA and WPU/CA blends increased with SA content, and the crosslinker concentration clearly indicated the dressing material hardness resulted from this simple blend strategy. The WPU/SA₃₀ electrospun nanofibrous blend contained porous membranes; it exhibited good mechanical strength with water-stable, water-absorbable (37.5 wt %), and moisture-permeable (25.1 g/m²-24 h) characteristics, suggesting our cost-effective material could function as an effective wound dressing material.

SUBMITTER: Lu WC 

PROVIDER: S-EPMC7761416 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature