Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia.
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ABSTRACT:
SUBMITTER: Hu S
PROVIDER: S-EPMC7761886 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia.
Hu Shaonan S Zhang Xinrui X Unger Michael M Patties Ina I Melzer Andreas A Landgraf Lisa L
Cells 20201203 12
Focused ultrasound (FUS) has become an important non-invasive therapy for solid tumor ablation via thermal effects. The cavitation effect induced by FUS is thereby avoided but applied for lithotripsy, support drug delivery and the induction of blood vessel destruction for cancer therapy. In this study, head and neck cancer (FaDu), glioblastoma (T98G), and prostate cancer (PC-3) cells were exposed to FUS by using an in vitro FUS system followed by single-dose X-ray radiation therapy (RT) or water ...[more]
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