The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women.
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ABSTRACT:
SUBMITTER: Khanal P
PROVIDER: S-EPMC7762041 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women.
Khanal Praval P He Lingxiao L Herbert Adam J AJ Stebbings Georgina K GK Onambele-Pearson Gladys L GL Degens Hans H Morse Christopher I CI Thomis Martine M Williams Alun G AG
Genes 20201205 12
There is a scarcity of studies that have investigated the role of multiple single nucleotide polymorphisms (SNPs) on a range of muscle phenotypes in an elderly population. The present study investigated the possible association of 24 SNPs with skeletal muscle phenotypes in 307 elderly Caucasian women (aged 60-91 years, 66.3 ± 11.3 kg). Skeletal muscle phenotypes included biceps brachii thickness, vastus lateralis cross-sectional areas, maximal hand grip strength, isometric knee extension and elb ...[more]
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