Ontology highlight
ABSTRACT:
SUBMITTER: Lee JS
PROVIDER: S-EPMC7762424 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Lee Jung-Sun JS Lee Eun-Ju EJ Lee Jae-Hyun JH Hong Seok-Chan SC Lee Chang-Keun CK Yoo Bin B Oh Ji-Seon JS Lee Sang-Hoon SH Kim Tae-Jong TJ Lee Seung-Hun SH Jo Sung-Sin SS Yoo Dae-Hyun DH Park Ye-Soo YS Kim Tae-Hwan TH Kim Yong-Gil YG
Journal of clinical medicine 20201207 12
<h4>Background</h4>Patients with ankylosing spondylitis (AS) have increased levels of protein phosphatase magnesium-dependent 1A (PPM1A) and autoantibodies. We evaluated the usefulness of serum anti-PPM1A antibodies as a biomarker for AS.<h4>Methods</h4>Serum samples from 58 AS patients were obtained from a multicenter registry prior to the initiation of anti-TNF agents. The serum levels of anti-PPM1A antibodies were measured using ELISA. Spinal radiographic progression was defined as an increas ...[more]