Ontology highlight
ABSTRACT:
SUBMITTER: Javed A
PROVIDER: S-EPMC7764114 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Cancers 20201209 12
Uveal melanoma has a high mortality rate following metastasis to the liver. Despite advances in systemic immune therapy, treatment of metastatic uveal melanoma (MUM) has failed to achieve long term durable responses. Barriers to success with immune therapy include the immune regulatory nature of uveal melanoma as well as the immune tolerant environment of the liver. To adequately harness the anti-tumor potential of the immune system, non-T cell-based approaches need to be explored. Natural Kille ...[more]