Ontology highlight
ABSTRACT:
SUBMITTER: Mamidi N
PROVIDER: S-EPMC7764530 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mamidi Narsimha N Velasco Delgadillo Ramiro Manuel RM Gonzáles Ortiz Aldo A Barrera Enrique V EV
Pharmaceutics 20201213 12
Herein, poly (<i>N</i>-(4-aminophenyl) methacrylamide))-carbon nano-onions (PAPMA-CNOs = f-CNOs) and anilinated-poly (ether ether ketone) (AN-PEEK) have synthesized, and AN-PEEK/f-CNOs composite thin films were primed via layer-by-layer (LbL) self-assembly for stimuli-responsive drug release. The obtained thin films exhibited pH-responsive drug release in a controlled manner; pH 4.5 = 99.2% and pH 6.5 = 59.3% of doxorubicin (DOX) release was observed over 15 days. Supramolecular π-π stacking int ...[more]