Next Generation Sequencing in Non-Small Cell Lung Cancer: Pitfalls and Opportunities.
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ABSTRACT:
SUBMITTER: Lazzari C
PROVIDER: S-EPMC7765222 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Next Generation Sequencing in Non-Small Cell Lung Cancer: Pitfalls and Opportunities.
Lazzari Chiara C Bulotta Alessandra A Cangi Maria Giulia MG Bucci Gabriele G Pecciarini Lorenza L Bonfiglio Silvia S Lorusso Vincenza V Ippati Stefania S Arrigoni Gianluigi G Grassini Greta G Doglioni Claudio C Gregorc Vanesa V
Diagnostics (Basel, Switzerland) 20201215 12
Lung cancer remains the first cause of cancer-related deaths worldwide. Thanks to the improvement in the knowledge of the biology of non-small cell lung cancer (NSCLC), patients' survival has significantly improved. A growing number of targetable molecular alterations have been identified. Next-generation sequencing (NGS) has become one of the methodologies entered in clinical practice and was recently recommended by the European society for medical oncology (ESMO) to perform a comprehensive mol ...[more]
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