Ontology highlight
ABSTRACT:
SUBMITTER: Okajima T
PROVIDER: S-EPMC7768282 | biostudies-literature | 2020 Nov/Dec
REPOSITORIES: biostudies-literature
Okajima Tomomi T Gu Yichen Y Teruya Rin-Ichiro RI Yano Sarasa S Taketomi Takumi T Sato Ban B Chiba Tomoki T Tsuruta Fuminori F
eNeuro 20201101 6
Microglia are resident macrophages that are critical for brain development and homeostasis. Microglial morphology is dynamically changed during postnatal stages, leading to regulating synaptogenesis and synapse pruning. Moreover, it has been well known that the shape of microglia is also altered in response to the detritus of the apoptotic cells and pathogens such as bacteria and viruses. Although the morphologic changes are crucial for acquiring microglial functions, the exact mechanism which c ...[more]