Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC7775893 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Journal of proteome research 20201112 1
In proteogenomic studies, genomic and transcriptomic variants are incorporated into customized protein databases for the identification of proteoforms, especially proteoforms with sample-specific variants. Most proteogenomic research has been focused on combining genomic or transcriptomic data with bottom-up mass spectrometry data. In the last decade, top-down mass spectrometry has attracted increasing attention because of its capacity to identify various proteoforms with alterations. However, t ...[more]