Ontology highlight
ABSTRACT:
SUBMITTER: Poulin JF
PROVIDER: S-EPMC7778471 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Poulin Jean-François JF Luppi Milagros Pereira MP Hofer Caitlyn C Caronia Giuliana G Hsu Pei-Ken PK Chan C Savio CS Awatramani Rajeshwar R
Developmental cell 20200601 6
Lineage tracing aims to identify the progeny of a defined population of dividing progenitor cells, a daunting task in the developing central nervous system where thousands of cell types are generated. In mice, lineage analysis has been accomplished using Cre recombinase to indelibly label a defined progenitor population and its progeny. However, the interpretation of historical recombination events is hampered by the fact that driver genes are often expressed in both progenitors and postmitotic ...[more]