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Candida Endocarditis in Patients with Candidemia: A Single-Center Experience of 14 Cases.

ABSTRACT: A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012-2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and 18F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had persistent candidemia for???3 days despite antifungal therapy.

SUBMITTER: Hitzenbichler F 

PROVIDER: S-EPMC7779412 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Candida Endocarditis in Patients with Candidemia: A Single-Center Experience of 14 Cases.

Hitzenbichler Florian F   Joha Tobias T   Simon Michaela M   Grosse Jirka J   Menhart Karin K   Hellwig Dirk D   Camboni Daniele D   Sag Sabine S   Sag Can Martin CM   Hanses Frank F   Salzberger Bernd B   Mohr Arno A  

Mycopathologia 20201009 6

A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012-2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and <sup>18</sup>F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had pe  ...[more]

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