Ontology highlight
ABSTRACT:
SUBMITTER: Dai XM
PROVIDER: S-EPMC7782074 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Dai Xiao-Man XM Zhang Yan-Hui YH Lin Xiao-Han XH Huang Xiao-Xing XX Zhang Yi Y Xue Chao-Rong CR Chen Wan-Nan WN Ye Jian-Xin JX Lin Xin-Jian XJ Lin Xu X
Molecular oncology 20201120 1
Salt-inducible kinase 2 (SIK2) is an important regulator in various intracellular signaling pathways related to apoptosis, tumorigenesis and metastasis. However, the involvement of SIK2 in gastric tumorigenesis and the functional linkage with gastric cancer (GC) progression remain to be defined. Here, we report that SIK2 was significantly downregulated in human GC tissues, and reduced SIK2 expression was associated with poor prognosis of patients. Overexpression of SIK2 suppressed the migration ...[more]