Ontology highlight
ABSTRACT: Background
Patients with chronic total coronary occlusions (CTO) are at increased risk for poor clinical outcomes. We aimed to determine the incidence of CTO percutaneous coronary intervention (PCI) and to identify CTO patients at risk for cardiac events in the nationwide Netherlands Heart Registration (NHR).Methods
We included all PCI procedures with ?1 CTO registered in the NHR from January 2015 to December 2018, excluding acute interventions. We used multivariable logistic regression of baseline characteristics to calculate the risk for events as odds ratios (OR) with 95% confidence intervals (CI).Results
Of the PCIs performed during the study period, 6.3% (8,343/133,042) were for CTOs, with the percentage increasing significantly over time from 5.9% in 2015 to 6.6% in 2018 (p?2) was identified as an independent predictor (OR 4.70, 95% CI 1.07-20.61, p?=?0.040). Among patients undergoing CTO-PCI, 1?year mortality was 3.7%, and independent predictors included renal insufficiency (OR 5.59, 95% CI 3.25-9.59, p?ConclusionCTO-PCI is still infrequently performed in the Netherlands. The most important predictor of mortality after CTO-PCI was renal insufficiency. Identification of patients at risk may help improve the prognosis of CTO patients in the future.
SUBMITTER: van Veelen A
PROVIDER: S-EPMC7782624 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
van Veelen A A Claessen B E P M BEPM Houterman S S Hoebers L P C LPC Elias J J Henriques J P S JPS Knaapen P P
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20201202 1
<h4>Background</h4>Patients with chronic total coronary occlusions (CTO) are at increased risk for poor clinical outcomes. We aimed to determine the incidence of CTO percutaneous coronary intervention (PCI) and to identify CTO patients at risk for cardiac events in the nationwide Netherlands Heart Registration (NHR).<h4>Methods</h4>We included all PCI procedures with ≥1 CTO registered in the NHR from January 2015 to December 2018, excluding acute interventions. We used multivariable logistic reg ...[more]