The Roles of ?? T Cells in Hematopoietic Stem Cell Transplantation.
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ABSTRACT:
SUBMITTER: Ye W
PROVIDER: S-EPMC7784584 | biostudies-literature | 2020 Jan-Dec
REPOSITORIES: biostudies-literature
Publications
The Roles of γδ T Cells in Hematopoietic Stem Cell Transplantation.
Ye Wanyi W Kong Xueting X Zhang Wenbin W Weng Zheng Z Wu Xiuli X
Cell transplantation 20200101
The αβ T-cell-depleted hematopoietic stem cell transplantation (HSCT) leads to lower relapse and better outcome, and may correlate strongly with expansion of donor-derived γδ T cells. γδ T cells play an important role in immune reconstitution and can exert a graft-versus-leukemia effect after HSCT. This review showed the recent literature on immune functions of γδ T cells after HSCT. The discrepancies between studies of γδ T cells in graft-versus-host disease may cause by its heterogeneous and v ...[more]
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