Ontology highlight
ABSTRACT:
SUBMITTER: Chen YP
PROVIDER: S-EPMC7784929 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Chen Yu-Pei YP Yin Jian-Hua JH Li Wen-Fei WF Li Han-Jie HJ Chen Dong-Ping DP Zhang Cui-Juan CJ Lv Jia-Wei JW Wang Ya-Qin YQ Li Xiao-Min XM Li Jun-Yan JY Zhang Pan-Pan PP Li Ying-Qin YQ He Qing-Mei QM Yang Xiao-Jing XJ Lei Yuan Y Tang Ling-Long LL Zhou Guan-Qun GQ Mao Yan-Ping YP Wei Chen C Xiong Ke-Xu KX Zhang Hong-Bo HB Zhu Shi-Da SD Hou Yong Y Sun Ying Y Dean Michael M Amit Ido I Wu Kui K Kuang Dong-Ming DM Li Gui-Bo GB Liu Na N Ma Jun J
Cell research 20200720 11
Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with extremely skewed ethnic and geographic distributions. Increasing evidence indicates that targeting the tumor microenvironment (TME) represents a promising therapeutic approach in NPC, highlighting an urgent need to deepen the understanding of the complex NPC TME. Here, we generated single-cell transcriptome profiles for 7581 malignant cells and 40,285 immune cells from fifteen primary NPC tumors and one normal sample. We revealed ma ...[more]