Ontology highlight
ABSTRACT:
SUBMITTER: Fenyves BG
PROVIDER: S-EPMC7785220 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Fenyves Bánk G BG Szilágyi Gábor S GS Vassy Zsolt Z Sőti Csaba C Csermely Peter P
PLoS computational biology 20201221 12
Graph theoretical analyses of nervous systems usually omit the aspect of connection polarity, due to data insufficiency. The chemical synapse network of Caenorhabditis elegans is a well-reconstructed directed network, but the signs of its connections are yet to be elucidated. Here, we present the gene expression-based sign prediction of the ionotropic chemical synapse connectome of C. elegans (3,638 connections and 20,589 synapses total), incorporating available presynaptic neurotransmitter and ...[more]