Ontology highlight
ABSTRACT:
SUBMITTER: Trevisan RO
PROVIDER: S-EPMC7787821 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Trevisan Rafael Obata RO Santos Malú Mateus MM Desidério Chamberttan Souza CS Alves Leandro Gomes LG de Jesus Sousa Thiago T de Castro Oliveira Letícia L Jaiswal Arun Kumar AK Tiwari Sandeep S Bovi Weslley Guimarães WG de Oliveira-Silva Mariana M Costa-Madeira Juliana Cristina JC Castellano Lúcio Roberto Cançado LRC Silva Marcos Vinicius MV Azevedo Vasco V Rodrigues Junior Virmondes V Oliveira Carlo José Freire CJF de Castro Soares Siomar S
Disease markers 20201210
Chagas disease is a neglected tropical disease caused by the parasite <i>Trypanosoma cruzi</i>. Despite the efforts and distinct methodologies, the search of antigens for diagnosis, vaccine, and drug targets for the disease is still needed. The present study is aimed at identifying possible antigens that could be used for diagnosis, vaccine, and drugs targets against <i>T. cruzi</i> using reverse vaccinology and molecular docking. The genomes of 28 <i>T. cruzi</i> strains available in GenBank (N ...[more]