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Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults.


ABSTRACT: This 9-month randomised, parallel, double-blind, single-centre, placebo-controlled study (PROBE, ISRCTN18030882) assessed the impact of probiotic supplementation on bodyweight. Seventy overweight Bulgarian participants aged 45-65 years with BMI 25-29.9 kg/m2 received a daily dose of the Lab4P probiotic comprising lactobacilli and bifidobacteria (50 billion cfu/day). Participants maintained their normal diet and lifestyle over the duration of the study. The primary outcome was change from baseline in body weight and secondary outcomes included changes in waist circumference, hip circumference and blood pressure. A significant between group decrease in body weight (3.16 kg, 95% CI 3.94, 2.38, p?

SUBMITTER: Michael DR 

PROVIDER: S-EPMC7788077 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults.

Michael D R DR   Davies T S TS   Jack A A AA   Masetti G G   Marchesi J R JR   Wang D D   Mullish B H BH   Plummer S F SF  

Scientific reports 20210106 1


This 9-month randomised, parallel, double-blind, single-centre, placebo-controlled study (PROBE, ISRCTN18030882) assessed the impact of probiotic supplementation on bodyweight. Seventy overweight Bulgarian participants aged 45-65 years with BMI 25-29.9 kg/m<sup>2</sup> received a daily dose of the Lab4P probiotic comprising lactobacilli and bifidobacteria (50 billion cfu/day). Participants maintained their normal diet and lifestyle over the duration of the study. The primary outcome was change f  ...[more]

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