Lack of Association of Spontaneous Coronary Artery Dissection With Autoimmune Disease.

ABSTRACT:

Background

Case reports and referral-based studies suggest spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and causes 2% to 4% of acute coronary syndromes.

Objectives

This study determined the association of SCAD with autoimmune diseases, together with incidence and recurrence, in a population-based study.

Methods

This case-control study took place from 1995 to 2018 within the Rochester Epidemiology Project. The study identified cases with SCAD from diagnosis codes and verified them using coronary angiography images, matching each case to 3 control subjects on age, sex, county, and years of medical history. Autoimmune disease history came from a validated, code-based definition. A multivariable logistic regression model calculated

SUBMITTER: Kronzer VL 

PROVIDER: S-EPMC7788566 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature