Unlabeled Far-Field Deeply Subwavelength Topological Microscopy (DSTM).

ABSTRACT: A nonintrusive far-field optical microscopy resolving structures at the nanometer scale would revolutionize biomedicine and nanotechnology but is not yet available. Here, a new type of microscopy is introduced, which reveals the fine structure of an object through its far-field scattering pattern under illumination with light containing deeply subwavelength singularity features. The object is reconstructed by a neural network trained on a large number of scattering events. In numerical experiments on imaging of a dimer, resolving powers better than λ/200, i.e., two orders of magnitude beyond the conventional "diffraction limit" of λ/2, are demonstrated. It is shown that imaging is tolerant to noise and is achievable with low dynamic range light intensity detectors. Proof-of-p

SUBMITTER: Pu T 

PROVIDER: S-EPMC7788582 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature