Dataset Information

Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial.

ABSTRACT:

Background

Pediatric Tuina has been widely used in children with acute diarrhea in China. However, due to the lack of high-quality clinical evidence, the benefit of Tuina as a therapy is not clear. We aimed to assess the effect of pediatric Tuina compared with sham Tuina as an add-on therapy in addition to usual care for 0-6-year-old children with acute diarrhea.

Methods

Eighty-six participants aged 0-6?years with acute diarrhea were randomized to receive pediatric Tuina plus usual care (n?=?43) or sham Tuina plus usual care (n?=?43). The primary outcomes were days of diarrhea from baseline and times of diarrhea on day 3. Secondary outcomes included a global change rating (GCR) and the number of days when the stool characteristics returned to normal. Adverse events were assessed.

Results

Pediatric Tuina was associated with a reduction in times of diarrhea on day 3 compared with sham Tuina in both ITT (crude RR, 0.73 [95% CI, 0.59-0.91]) and PP analyses (crude RR, 0.66 [95% CI, 0.53-0.83]). However, the results were not significant when we adjusted for social demographic and clinical characteristics. No significant difference was found between groups in days of diarrhea, global change rating, or number of days when the stool characteristics returned to normal.

Conclusions

In children aged 0-6?years with acute diarrhea, pediatric Tuina showed significant effects in terms of reducing times of diarrhea compared with sham Tuina. Studies with larger sample sizes and adjusted trial designs are warranted to further evaluate the effect of pediatric Tuina therapy.

Trial registration

Clinicaltrials.gov, Identifier: NCT03005821 , Data of registration: 2016-12-29.

SUBMITTER: Lu T

PROVIDER: S-EPMC7788799 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial.

Lu Taoying T Yin Lingjia L Chen Ruoqing R Zhang Huiyan H Cai Jianxiong J Li Meiling M Dai Lin L Zhu Conghao C Zhang Yongping Y Xiang Feng F Wang Li L Li Lu L Wang Lixin L Wu Darong D

Health and quality of life outcomes 20210106 1

<h4>Background</h4>Pediatric Tuina has been widely used in children with acute diarrhea in China. However, due to the lack of high-quality clinical evidence, the benefit of Tuina as a therapy is not clear. We aimed to assess the effect of pediatric Tuina compared with sham Tuina as an add-on therapy in addition to usual care for 0-6-year-old children with acute diarrhea.<h4>Methods</h4>Eighty-six participants aged 0-6 years with acute diarrhea were randomized to receive pediatric Tuina plus usua ...[more]

PMID: 33407547

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Project description:Background: Medication and behavior therapy are the conventional treatments for attention deficit hyperactivity disorder (ADHD), but they have limitations for preschool children. Evidence suggests that pediatric tuina, which is a modality of traditional Chinese medicine, might have beneficial effects on this condition.Objective: To assess the feasibility of conducting an RCT in terms of recruitment, use, and acceptability of the parent-administered pediatric tuina for ADHD symptoms in preschoolers.Methods: It is a single-center, two-arm, parallel, open-label, pilot randomized controlled trial (RCT). Sixty children with pre-specified ADHD symptoms (hyperactivity, anxiety, and sleep disturbance) together with one of their parents will be recruited and randomized into two groups at a 1:1 ratio. Parents in the parent-administered tuina group (intervention group, n = 30) will attend an online training program to learn pediatric tuina skills for ADHD symptoms and conduct this treatment on their children at home. Parents in the parent-child interaction group (comparison group, n = 30) will attend an online training about progressive muscle relaxation exercise and do this exercise with their children at home. Additional teaching materials will be provided to the participants in both groups. Both interventions should be carried out every other day during a 2-month treatment period, with each time around 20?min. Assessment will be performed at baseline, week 4, and week 8. The primary outcome measure is the Swanson, Nolan, and Pelham parent scale; the secondary outcomes include preschool anxiety scale, children's sleep habits questionnaire, and parental stress scale. A process evaluation embedded within the outcome evaluation will be performed. Differences in the scale scores and test parameters between groups will be examined using a linear mixed-effects model. Qualitative data will be analyzed using thematic content analysis, facilitated by QSR NVivo.Discussion: This study will provide evidence on the acceptability and feasibility of pediatric tuina for ADHD in preschool children. The process evaluation will help to better understand the facilitators and barriers of the intervention functioning.Trial registration: The study was registered at ClinicalTrials.gov (Identifier: NCT04237259 ) on 14 February 2020. Protocol version: 2; date, 23 June 2020.

Dataset Information

Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial.

Background

Methods

Results

Conclusions

Trial registration

Publications

Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial.

Similar Datasets

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