Dataset Information

Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank.

ABSTRACT:

Objective

No recent large studies have described the distribution of vitamin D status in the UK. Understanding the epidemiology of vitamin D deficiency is important to inform targeted public health recommendations. This study aimed to investigate the distribution of factors associated with serum vitamin D status in a large national cohort.

Design

A cross-sectional study.

Setting

The UK Biobank, a prospective cohort study following the health and well-being of middle-aged and older adults recruited between 2006 and 2010.

Participants

A total of 449 943 participants aged 40-69 years with measured serum vitamin D status were eligible for the analysis. Participants completed a questionnaire about sex, age, ethnic background, vitamin D supplementation, smoking, drinking and socioeconomic status.

Primary and secondary outcome measures

We investigated the distribution of serum vitamin D status and the association between demographic factors and vitamin D deficiency or insufficiency. Vitamin D deficiency was defined as a serum 25-hydroxyvitamin D level <25 nmol/L. Multivariable logistic regression was used to assess the association between demographic factors and vitamin D status.

Results

Asian (n=4297/8000, 53.7%) and black (n=2459/7046, 34.9%) participants had a higher proportion of vitamin D deficiency than white participants (n=50 920/422 907, 12%). During spring and winter, the proportion of vitamin D deficiency was higher across the UK and higher in the north than in the south. Male sex, abnormal body mass index, non-white ethnic backgrounds, smoking and being more socioeconomically deprived were associated with higher odds of vitamin D deficiency. Increasing age, taking vitamin D supplements and drinking alcohol were associated with lower odds of deficiency.

Conclusions

Vitamin D status varied among different ethnic groups and by season and geographical area within the UK. Taking supplements was associated with a lower risk of vitamin D deficiency. These findings support the vitamin D supplementation recommendations of Public Health England.

SUBMITTER: Lin LY

PROVIDER: S-EPMC7789460 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank.

Lin Liang-Yu LY Smeeth Liam L Langan Sinead S Warren-Gash Charlotte C

BMJ open 20210106 1

<h4>Objective</h4>No recent large studies have described the distribution of vitamin D status in the UK. Understanding the epidemiology of vitamin D deficiency is important to inform targeted public health recommendations. This study aimed to investigate the distribution of factors associated with serum vitamin D status in a large national cohort.<h4>Design</h4>A cross-sectional study.<h4>Setting</h4>The UK Biobank, a prospective cohort study following the health and well-being of middle-aged an ...[more]

PMID: 33408196

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Dataset Information

Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank.

Objective

Design

Setting

Participants

Primary and secondary outcome measures

Results

Conclusions

Publications

Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank.

Similar Datasets

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