Dataset Information

HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China.

ABSTRACT:

Background

This cohort study was designed to investigate the prevalence of and potential risk factors of HEV infection in a large multi-ethnic youth cohort in China.

Methods

Blood samples were collected from participants (n?=?6269) and serum was isolated. All serum samples were tested for anti-HEV IgG, anti-HEV IgM antibodies using commercial enzyme immunoassay kits (Wantai Biological Pharmacy Enterprise, Beijing, China).

Results

The overall rate of anti-HEV IgG and anti-HEV IgM prevalence was 4.78% and 0.14%, 0.03% were positive for both anti-HEV IgG and anti-HEV IgM antibodies. Anti-HEV IgG positivity is significantly higher in females (5.27%) compared to males (4.14%) (P?=?0.028). Anti-HEV IgG prevalence is significantly (P?=?0.0001) higher in Dong (17.57%), Miao (12.23%), Yi (11.04%), Gelao (9.76%), and Bai (10.00%) compared to other ethnic groups. It is significantly higher in Guizhou (11.4%), Sichuan (10.1%), Yunnan (9.3%), and Guangxi (6.9%) than that other province. We found that ethnicity and provincial background are significantly associated with HEV infection in this cohort.

Conclusion

This study provides comprehensive information on HEV prevalence in multi-ethnic populations in China. However, our study only focused on a youth population from different provinces of China. Future studies are recommended to investigate HEV prevalence in other age groups of the ethnic populations.

SUBMITTER: Li H

PROVIDER: S-EPMC7789705 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China.

Li Huixia H Zhang Yinxia Y Ma Zhongren Z Liu Zewen Z Ikram Aqsa A Liu Lijiang L Zhao Guoqin G Pan Qiuwei Q Baloch Zulqarnain Z

Virology journal 20210106 1

<h4>Background</h4>This cohort study was designed to investigate the prevalence of and potential risk factors of HEV infection in a large multi-ethnic youth cohort in China.<h4>Methods</h4>Blood samples were collected from participants (n = 6269) and serum was isolated. All serum samples were tested for anti-HEV IgG, anti-HEV IgM antibodies using commercial enzyme immunoassay kits (Wantai Biological Pharmacy Enterprise, Beijing, China).<h4>Results</h4>The overall rate of anti-HEV IgG and anti-HE ...[more]

PMID: 33407606

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Dataset Information

HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China.

Background

Methods

Results

Conclusion

Publications

HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China.

Similar Datasets

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