Ontology highlight
ABSTRACT:
SUBMITTER: Lin D
PROVIDER: S-EPMC7790544 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Lin Dongdong D Yalamanchili Hima B HB Zhang Xinmin X Lewis Nathan E NE Alves Christina S CS Groot Joost J Arnsdorf Johnny J Bjørn Sara P SP Wulff Tune T Voldborg Bjørn G BG Zhou Yizhou Y Zhang Baohong B
PLoS computational biology 20201222 12
Chinese hamster ovary (CHO) cell lines are widely used in industry for biological drug production. During cell culture development, considerable effort is invested to understand the factors that greatly impact cell growth, specific productivity and product qualities of the biotherapeutics. While high-throughput omics approaches have been increasingly utilized to reveal cellular mechanisms associated with cell line phenotypes and guide process optimization, comprehensive omics data analysis and m ...[more]