Criticality: A New Concept of Severity of Illness for Hospitalized Children.

ABSTRACT:

Objectives

To validate the conceptual framework of "criticality," a new pediatric inpatient severity measure based on physiology, therapy, and therapeutic intensity calibrated to care intensity, operationalized as ICU care.

Design

Deep neural network analysis of a pediatric cohort from the Health Facts (Cerner Corporation, Kansas City, MO) national database.

Setting

Hospitals with pediatric routine inpatient and ICU care.

Patients

Children cared for in the ICU (n = 20,014) and in routine care units without an ICU admission (n = 20,130) from 2009 to 2016. All patients had laboratory, vital sign, and medication data.

Interventions

None.

Measurements and main results

A calibrated, deep neural network used physiology (laboratory tests and vital signs)

SUBMITTER: Rivera EAT 

PROVIDER: S-EPMC7790867 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature