Dataset Information
Serological diagnosis and prevalence of HIV-1 infection in Russian metropolitan areas.
Ontology highlight
ABSTRACT: Background
HIV infection is a major health problem in Russia. We aimed to assess HIV prevalence in different population groups and to compare the characteristics of 4th generation immunoassays from Abbott, Bio-Rad, Vector-Best, Diagnostic Systems, and Medical Biological Unit.Methods
The study included 4452 individuals from the general population (GP), 391 subjects at high risk of HIV infection (HR) and 699 with potentially interfering conditions. HIV positivity was confirmed by immunoblot and by HIV RNA, seroconversion and virus diversity panels were also used. HIV avidity was employed to assess recent infections.Results
The prevalence in GP was 0.40%, higher in males (0.62%) and in people aged ConclusionHIV infection rate in the high-risk groups suggests that awareness and screening campaigns should be enhanced. Fourth generation assays are adequate but performance differences must be considered.
SUBMITTER: Kireev DE
PROVIDER: S-EPMC7791727 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Serological diagnosis and prevalence of HIV-1 infection in Russian metropolitan areas.
BMC infectious diseases 20210107 1
<h4>Background</h4>HIV infection is a major health problem in Russia. We aimed to assess HIV prevalence in different population groups and to compare the characteristics of 4th generation immunoassays from Abbott, Bio-Rad, Vector-Best, Diagnostic Systems, and Medical Biological Unit.<h4>Methods</h4>The study included 4452 individuals from the general population (GP), 391 subjects at high risk of HIV infection (HR) and 699 with potentially interfering conditions. HIV positivity was confirmed by i ...[more]
