Dataset Information

Associations between substandard housing and depression: insights from the Korea welfare panel study.

ABSTRACT:

Background

Housing is an important social determinant of health. Poor housing conditions are associated with a wide range of health conditions, including mental health. The study aimed to investigate the association between substandard housing and depression.

Methods

We used panel data collected by the Korea Welfare Panel Study and a sample drawn from waves 11 (2016) to 13 (2018). Substandard housing was defined via three criteria: the minimum residential area and number of rooms by application, essential facility standards, and environmental standards. Depression was measured with the CESD-11. A generalized estimating equation model was used to investigate associations between substandard housing and CESD-11 scores.

Results

Participants living in substandard housing have higher depression scores (male: ??=?0.63, female: ??=?0.40) than participants who do not live in substandard housing. Participants who do not meet environmental standards have higher depression scores (male: ??=?0.85, female: ??=?0.66) than participants who do not live in substandard housing; the findings are seen in both men and women.

Conclusion

This study identified an association between substandard housing and depression by gender, and the results were significant. We found that among the three criteria, environmental standards are most likely to be associated with depression. In practical terms, we should consider improving environmental factors of housing to mitigate mental health issues related to substandard housing.

SUBMITTER: Kim S

PROVIDER: S-EPMC7792032 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Associations between substandard housing and depression: insights from the Korea welfare panel study.

Kim Selin S Jeong Wonjeong W Jang Bich Na BN Park Eun-Cheol EC Jang Sung-In SI

BMC psychiatry 20210107 1

<h4>Background</h4>Housing is an important social determinant of health. Poor housing conditions are associated with a wide range of health conditions, including mental health. The study aimed to investigate the association between substandard housing and depression.<h4>Methods</h4>We used panel data collected by the Korea Welfare Panel Study and a sample drawn from waves 11 (2016) to 13 (2018). Substandard housing was defined via three criteria: the minimum residential area and number of rooms ...[more]

PMID: 33413249

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Project description:Importance:Germline pathogenic variants in BRCA1 and BRCA2 predispose to an increased lifetime risk of breast cancer. However, the relevance of germline variants in other genes from multigene hereditary cancer testing panels is not well defined. Objective:To determine the risks of breast cancer associated with germline variants in cancer predisposition genes. Design, Setting, and Participants:A study population of 65?057 patients with breast cancer receiving germline genetic testing of cancer predisposition genes with hereditary cancer multigene panels. Associations between pathogenic variants in non-BRCA1 and non-BRCA2 predisposition genes and breast cancer risk were estimated in a case-control analysis of patients with breast cancer and Exome Aggregation Consortium reference controls. The women underwent testing between March 15, 2012, and June 30, 2016. Main Outcomes and Measures:Breast cancer risk conferred by pathogenic variants in non-BRCA1 and non-BRCA2 predisposition genes. Results:The mean (SD) age at diagnosis for the 65 057 women included in the analysis was 48.5 (11.1) years. The frequency of pathogenic variants in 21 panel genes identified in 41?611 consecutively tested white women with breast cancer was estimated at 10.2%. After exclusion of BRCA1, BRCA2, and syndromic breast cancer genes (CDH1, PTEN, and TP53), observed pathogenic variants in 5 of 16 genes were associated with high or moderately increased risks of breast cancer: ATM (OR, 2.78; 95% CI, 2.22-3.62), BARD1 (OR, 2.16; 95% CI, 1.31-3.63), CHEK2 (OR, 1.48; 95% CI, 1.31-1.67), PALB2 (OR, 7.46; 95% CI, 5.12-11.19), and RAD51D (OR, 3.07; 95% CI, 1.21-7.88). Conversely, variants in the BRIP1 and RAD51C ovarian cancer risk genes; the MRE11A, RAD50, and NBN MRN complex genes; the MLH1 and PMS2 mismatch repair genes; and NF1 were not associated with increased risks of breast cancer. Conclusions and Relevance:This study establishes several panel genes as high- and moderate-risk breast cancer genes and provides estimates of breast cancer risk associated with pathogenic variants in these genes among individuals qualifying for clinical genetic testing.

Dataset Information

Associations between substandard housing and depression: insights from the Korea welfare panel study.

Background

Methods

Results

Conclusion

Publications

Associations between substandard housing and depression: insights from the Korea welfare panel study.

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