Ontology highlight
ABSTRACT:
SUBMITTER: Szeto C
PROVIDER: S-EPMC7793522 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Szeto Christopher C Lobos Christian A CA Nguyen Andrea T AT Gras Stephanie S
International journal of molecular sciences 20201223 1
T cells are a critical part of the adaptive immune system that are able to distinguish between healthy and unhealthy cells. Upon recognition of protein fragments (peptides), activated T cells will contribute to the immune response and help clear infection. The major histocompatibility complex (MHC) molecules, or human leukocyte antigens (HLA) in humans, bind these peptides to present them to T cells that recognise them with their surface T cell receptors (TCR). This recognition event is the firs ...[more]