Ontology highlight
ABSTRACT:
SUBMITTER: Piris-Villaespesa M
PROVIDER: S-EPMC7794224 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Piris-Villaespesa Miguel M Álvarez-Larrán Alberto A Saez-Marín Adolfo A Nuñez-Torrón Claudia C Muñoz-Martin Gloria G Sánchez Ricardo R Del Castillo Francisco J FJ Villarrubia Jesús J Lopez-Jimenez Javier J Martinez-Lopez Joaquin J Garcia-Gutierrez Valentin V
Scientific reports 20210108 1
In 2016, the WHO included haemoglobin values within normal ranges as a diagnostic criterion for Polycythaemia Vera (PV). Since then, concerns have arisen that a large number of patients are undergoing unnecessary screening for PV. To address this issue, we estimated the prevalence of JAK2 p.V617F in individuals with elevated haemoglobin or haematocrit and developed and validated a screening algorithm for PV. A total of 15,366 blood counts performed in seven non-consecutive days were reviewed, of ...[more]