Ontology highlight
ABSTRACT:
SUBMITTER: Ahn JW
PROVIDER: S-EPMC7795021 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20201226 1
Macrophage-derived foam cells play critical roles in the initiation and progression of atherosclerosis. Activated macrophages and foam cells are important biomarkers for targeted imaging and inflammatory disease therapy. Macrophages also express the dectin-1 receptor, which specifically recognizes β-glucan (Glu). Here, we prepared photoactivatable nanoagents (termed Glu/Ce6 nanocomplexes) by encapsulating hydrophobic chlorin e6 (Ce6) within the triple-helix structure of Glu in aqueous condition. ...[more]