Ontology highlight
ABSTRACT:
SUBMITTER: Nedoszytko B
PROVIDER: S-EPMC7795405 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Nedoszytko Boguslaw B Arock Michel M Lyons Jonathan J JJ Bachelot Guillaume G Schwartz Lawrence B LB Reiter Andreas A Jawhar Mohamad M Schwaab Juliana J Lange Magdalena M Greiner Georg G Hoermann Gregor G Niedoszytko Marek M Metcalfe Dean D DD Valent Peter P
International journal of molecular sciences 20210102 1
Mastocytosis is a rare and complex disease characterized by expansion of clonal mast cells (MC) in skin and/or various internal organ systems. Involvement of internal organs leads to the diagnosis of systemic mastocytosis (SM). The WHO classification divides SM into indolent SM, smoldering SM and advanced SM variants, including SM with an associated hematologic neoplasm, aggressive SM, and MC leukemia. Historically, genetic analysis of individuals with pure cutaneous mastocytosis (CM) and SM hav ...[more]